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2017•European Journal of Medicinal ChemistryOpen access

Recent advances in the search for novel 5-lipoxygenase inhibitors for the treatment of asthma

Ferdinando F. Bruno, Giuseppe Spaziano, Angela Liparulo, Fiorentina Roviezzo, Seyed Mohammed Nabavi, Antoni Sureda, Rosanna Filosa, Bruno D'Agostino

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Key concepts: Zileuton, Bronchoconstriction, Arachidonate 5-lipoxygenase, Asthma, Chemistry, Leukotriene, Arachidonic acid metabolism, Lipoxygenase

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