The role of different fluoridated dentifrice formulations in enamel remineralisation in vitro

Aim: The aim of this study is to investigate the effect of commercially available dentifrices with different fluoride formula on remineralisation of enamel surface. Design: Enamel blocks were ground flat with water-cooled carborundum discs (320, 600 and 1200 grit) and randomly divided into seven groups. Specimens were subjected to a daily cycling regime comprising: two 1-min treatments ; one before and one after the demineralisation period of 6 and 18 h remineralisation in artificial saliva. During the pH cycling regimen each of the those seven groups were received different treatment: fluoride dentifrice Sensodyne Rapid (1040 ppm NaF), Colgate Total (1100 ppm NaF), Parodontax fluoride (1400 ppm NaF), Sensodyne fluoride (1400 ppm NaF), Pronamel Sensodyne (1450 ppm NaF), Elmex- GABA International (1250 ppm F Amine fluoride) and fluoride free Detartrine Paste (Septodont). The surface microhardness (SMH) of the specimens was determined at baseline and after 12 days using HMV-2000 (50 g, 490.3 mN, 10 s) (Shimadzu, Japan). Results: All specimens groups treated with fluorides showed increase in SMH compared to control group. Pronamel, Sensodyne F and Sensodyne Rapid were statistically superior to other fluoride dentifrices and a fluoride-free control after 12 days pH-cycling regime. Rates of enamel microhardness at baseline and after 12 days cycling treated with Parodontax obtained increase in SMH, but it was not statistically significant (P > 0.05). Conclusion: The results obtained in the present study showed that high fluoride toothpastes (1450 ppm) effectively inhibit demineralization under experimental conditions.