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Percent of Cytopathic Effect in Vero vs Vero-76 cells

Taylor Redding, Skot Neilson, Craig W. Day, Jonna B. Westover

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Abstract

Vero cells and Vero-76 cells are both used to evaluate the antiviral effect of drugs in vitro. This study tested whether Vero and Vero-76 cells yield similar cytopathic effects when inoculated with yellow fever Virus (YFV) or Dengue Virus(DV). Each virus was plated on replicated 96 well plates of Vero and Vero-76 cells with different cell concentrations. The two cells lines did not give significantly different results for most cell and virus concentrations.

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What this paper is about

Vero cells and Vero-76 cells are both used to evaluate the antiviral effect of drugs in vitro. This study tested whether Vero and Vero-76 cells yield similar cytopathic effects when inoculated with yellow fever Virus (YFV) or Dengue Virus(DV). Each virus was plated on replicated 96 well plates of Vero and Vero-76 cells with different cell concentrations. The two cells lines did not give significantly different results for most cell and virus concentrations.

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Available abstract

Vero cells and Vero-76 cells are both used to evaluate the antiviral effect of drugs in vitro. This study tested whether Vero and Vero-76 cells yield similar cytopathic effects when inoculated with yellow fever Virus (YFV) or Dengue Virus(DV). Each virus was plated on replicated 96 well plates of Vero and Vero-76 cells with different cell concentrations. The two cells lines did not give significantly different results for most cell and virus concentrations.

Key concepts: Vero cell, Virology, Biology, Virus

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