2017•Journal of the Chinese Chemical SocietyRequires access

One-Pot Synthesis of 2,4,5-Triphenyl Imidazoles from 1,2-Diols as Key Reagents

Narasashetty Jagadishbabu, Kalegowda Shivashankar

Abstract

A simple one-pot procedure for the preparation of 2,4,5-triphenyl imidazole derivatives is presented. The procedure involves the lead tetraacetate oxidation of 1,2-diols to give aldehydes in situ, which then undergo a three-component reaction with benzil and ammonium acetate to yield the imidazole derivatives.

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Key concepts: Chemistry, Benzil, Imidazole, Ammonium acetate, Yield (engineering), Reagent, Organic chemistry, Combinatorial chemistry