Investigation of Liver Volume Change of Primary Biliary Cirrhosis Compared to Hepatitis B Virus-Related Cirrhosis by 64-Slice Spiral CT

Objective To explore the value of 64-slice spiral CT on the change of liver volume in patients with primary biliary cirrhosis. Methods Collecting 48 patients with PBC,64 patients with hepatitis B virus-related cirrhosis and 52 patients with no liver disease as control group. Enhanced CT Abdomen was performed in each patient and the axial images of portal venous phase were transferred to GE Advantage Workstation 4. 4. The standardized liver volumes of each group were analyzed with SPSS 15. 0. Results( 1) The differences of the liver volume and the standardized liver volume by CT have statistical significance in these groups( F = 7. 435、P = 0. 024,F = 4. 862、P = 0. 012);( 2) Compare the liver volume and the standardized liver volume between every two groups,differences were observed between the PBC group and HBC group. The HBC group and control group have statistical significance( P 0. 050). Conclusion PBC tends to occur in females. In the decompensated period,the liver volume shrinking is not significant and part of them having diffuse enlargement.