Progress in diagnosis and treatment of lung cancer in the elderly
Shengping Shen, Shun Lü
Abstract
Shengping Shen, Shun Lü
Abstract
Lung cancer is the most common cancer and the leading cause of cancer-related deaths in the world. More than 50 % of advanced NSCLC are diagnosed in patients older than age 65 years. Aging is inextricably associated with decreases in marrow reserve, drug clearance, and lean body mass. Elderly cancer patients often present with medical and physiologic challenges that make the selection of their optimal treatment daunting. This article reviews the progress in diagnosis and treatment of lung cancer in the elderly in recent years. Key words: Lung neoplasms; Diagnosis; Therapy
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Lung cancer is the most common cancer and the leading cause of cancer-related deaths in the world. More than 50 % of advanced NSCLC are diagnosed in patients older than age 65 years. Aging is inextricably associated with decreases in marrow reserve, drug clearance, and lean body mass. Elderly cancer patients often present with medical and physiologic challenges that make the selection of their optimal treatment daunting. This article reviews the progress in diagnosis and treatment of lung cancer in the elderly in recent years. Key words: Lung neoplasms; Diagnosis; Therapy
Key concepts: Lung cancer, Medicine, Cancer, Lung, Treatment of lung cancer, Intensive care medicine, Lean body mass, Oncology