Pre- & post-operative factors affecting speech perception in adult cochlear implant users

A common feature of published studies of cochlear implantation is a very wide range of performance levels within a group of patients. It is well-established that preoperative factors including duration of deafness, age at implantation, duration of implant use and etiology can have statistically significant effects on speech perception with a cochlear implant, but they do not account for a very high proportion of the variance within groups of implant users. The biological basis for these effects is not well established. For example, it is unclear whether the effect of duration of deafness is due to a decrease in the number of surviving ganglion cells in the cochlea, to the detailed distribution of functional neurons within the cochlea, to degeneration of nerve function at higher auditory centers, to plastic neural effects during deafness, or to a combination of all of these mechanisms. Data for other factors may cast some light on these possibilities.