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2017•European Journal of Medicinal ChemistryOpen access

Design, synthesis and biological evaluation of thienopyrimidine hydroxamic acid based derivatives as structurally novel histone deacetylase (HDAC) inhibitors

Jiang Wang, Mingbo Su, Tingting Li, Anhui Gao, Wei Yang, Sheng Li, Yi Zang, Jia Xuan Li, Hong Shu Liu

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Key concepts: Hydroxamic acid, Chemistry, HDAC6, Acetylation, HDAC8, Histone deacetylase, IC50, HDAC3

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