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2014•Bioorganic & Medicinal ChemistryOpen access

Design and synthesis of novel and highly-active pan-histone deacetylase (pan-HDAC) inhibitors

Toshihiko Tashima, Hiroaki Murata, Hidehiko Kodama

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Key concepts: Chemistry, Hydroxamic acid, Histone deacetylase, HDAC8, HDAC6, HDAC1, Histone deacetylase 2, Pharmacology

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Design and synthesis of novel and highly-active pan-histone deacetylase (pan-HDAC) inhibitors — Research Paper | ScholarLens