ScholarLens Back to search
2016•Journals & Books Hosting (International Knowledge Sharing Platform)Open access

Evaluate of Antioxidant Enzymes Superoxide Dismutase, Glutathione Peroxidase and Catalase Levels in Asthma Patients

Murtadha F. Hassan Al-Kinani, Sahera Gh. Sayyah

Open full text 2 citations

Abstract

Asthma is a chronic airway inflammation which involves the interplay of different types of inflammatory cells and cytokines in the airway.The present study evaluates the antioxidant enzymes including superoxide dismutase, glutathione peroxidase and Catalase levels.The results showed a significant increase (P˂0.05) in erythrocyte superoxide dismutase (SOD) activity in asthmatic patients as compared to control group.While there were a significant decrease in glutathione peroxidase (GPx) (P˂0.05) and Catalase (CAT) (P˂0.05)activities in patients as compared to control group, in accordance with age, severity, smoking and family history.But, there were no significant changes in the enzymes levels between males and females.The results indicated that antioxidant enzymes could play an important role in gen-environment interaction in complex lung disease such as asthma.

Open-access reader

About this research paper

What this paper is about

Asthma is a chronic airway inflammation which involves the interplay of different types of inflammatory cells and cytokines in the airway.The present study evaluates the antioxidant enzymes including superoxide dismutase, glutathione peroxidase and Catalase levels.The results showed a significant increase (P˂0.05) in erythrocyte superoxide dismutase (SOD) activity in asthmatic patients as compared to control group.While there were a significant decrease in glutathione peroxidase (GPx) (P˂0.05) and Catalase (CAT) (P˂0.05)activities in patients as compared to control group, in accordance with age, severity, smoking and family history.But, there were no significant changes in the enzymes levels between males and females.The results indicated that antioxidant enzymes could play an important role in gen-environment interaction in complex lung disease such as asthma.

Why it matters

OpenAlex reports 2 citations for this work. Citation counts describe recorded attention and do not establish research quality.

Key contribution

A contribution statement is not available in the OpenAlex record.

Method / approach

Method details are not available in the OpenAlex metadata.

Main findings

Findings are not separately available in the OpenAlex metadata.

Limitations

Limitations are not available in the OpenAlex metadata.

Applications

Application details are not available in the OpenAlex metadata.

Available abstract

Asthma is a chronic airway inflammation which involves the interplay of different types of inflammatory cells and cytokines in the airway.The present study evaluates the antioxidant enzymes including superoxide dismutase, glutathione peroxidase and Catalase levels.The results showed a significant increase (P˂0.05) in erythrocyte superoxide dismutase (SOD) activity in asthmatic patients as compared to control group.While there were a significant decrease in glutathione peroxidase (GPx) (P˂0.05) and Catalase (CAT) (P˂0.05)activities in patients as compared to control group, in accordance with age, severity, smoking and family history.But, there were no significant changes in the enzymes levels between males and females.The results indicated that antioxidant enzymes could play an important role in gen-environment interaction in complex lung disease such as asthma.

Key concepts: Superoxide dismutase, Glutathione peroxidase, Catalase, Antioxidant, Malondialdehyde, Reactive oxygen species, Dismutase, Chemistry

Related papers

Related paper 1Related paper 2Related paper 3
Back to paper searchBrowse research topicsOriginal source
Evaluate of Antioxidant Enzymes Superoxide Dismutase, Glutathione Peroxidase and Catalase Levels in Asthma Patients — Research Paper | ScholarLens