Studies in Brucella Infections

This bulletin contains five papers, on nonspecific agglutination in the Brucella group, the chemical examination of an avirulent strain of Brucella abortus, a study of Brucella abortusinfected tissues as immunizing agents against Brucella infection in the guinea-pig, a method for measuring the opsonocytophagic power of the blood of cattle for Brucella, and undulant fever: specific treatment with brucellin and procedures for diagnosis. These reports record the continuation of the splendid studies on brucellosis made by Huddleson and his collaborators at Michigan State College. The first study reveals that partially or completely dissociated strains of Brucella are unreliable as antigens for the agglutination test. There are long intervals during which dissociated strains are heat stable. The thermo-agglutination test serves only as an approximate means of detecting rough and dissociated variants of Brucella. It cannot be depended on entirely as a routine test for the selection of normal cultures for use as