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Enhancement of phagocytosis in bovine milk leukocytes in vitro.

F. H. S. Newbould

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Abstract

The data presented show a highly significant increase in numbers of bovine milk leukocytes, obtained from mammary glands of 13 cows irritated by sterile distilled water, which ingested staphylococci in four hr when 0.04% glucose was added to the leukocyte: staphylococci mixture. This increase was of the same order as that resulting from the addition of 5% of bovine anti-staphylococcal serum containing 16 I U of anti-alpha haemolysin. Nonimmune serum produced no enhancement. Cells from two other cows did not respond to either glucose or immune serum.

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What this paper is about

The data presented show a highly significant increase in numbers of bovine milk leukocytes, obtained from mammary glands of 13 cows irritated by sterile distilled water, which ingested staphylococci in four hr when 0.04% glucose was added to the leukocyte: staphylococci mixture. This increase was of the same order as that resulting from the addition of 5% of bovine anti-staphylococcal serum containing 16 I U of anti-alpha haemolysin. Nonimmune serum produced no enhancement. Cells from two other cows did not respond to either glucose or immune serum.

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Available abstract

The data presented show a highly significant increase in numbers of bovine milk leukocytes, obtained from mammary glands of 13 cows irritated by sterile distilled water, which ingested staphylococci in four hr when 0.04% glucose was added to the leukocyte: staphylococci mixture. This increase was of the same order as that resulting from the addition of 5% of bovine anti-staphylococcal serum containing 16 I U of anti-alpha haemolysin. Nonimmune serum produced no enhancement. Cells from two other cows did not respond to either glucose or immune serum.

Key concepts: Phagocytosis, Hemolysin, In vitro, Bovine milk, Distilled water, Immune system, Mastitis, Microbiology

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