Estrogenic Activity of Feces and Urine following Oral Administration of Diethylstilbestrol to Lambs

Four lambs were placed on metabolism studies and fed two different levels of stilbestrol. At the 1 mg. level per lamb per day, 51% of the stilbestrol appeared in the feces and 25% in the urine. At the 2 mg. level, 45% appeared in the feces and 39% in the urine. Combining both levels of feeding, 80% of the fed stilbestrol was recovered in the urine and feces. The possible fate of the remaining 20% is briefly discussed.