1954Experimental Biology and MedicineRequires access

Hemolytic Activity of Diethylstilbestrol and Some Steroid Hormones.

I Tateno, Edwin D. Kilbourne

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Abstract

Diethylstilbestrol, progesterone and DOCA induced in vitro hemolysis of human “O” erythrocytes. The hemolytic activity of stilbestrol was modified by temperature, pH, human serum, or the addition of non-hemolytic corticosteroids. Prolytic loss of potassium from stilbestrol-treated cells was demonstrated.

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Diethylstilbestrol, progesterone and DOCA induced in vitro hemolysis of human “O” erythrocytes. The hemolytic activity of stilbestrol was modified by temperature, pH, human serum, or the addition of non-hemolytic corticosteroids. Prolytic loss of potassium from stilbestrol-treated cells was demonstrated.

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Available abstract

Diethylstilbestrol, progesterone and DOCA induced in vitro hemolysis of human “O” erythrocytes. The hemolytic activity of stilbestrol was modified by temperature, pH, human serum, or the addition of non-hemolytic corticosteroids. Prolytic loss of potassium from stilbestrol-treated cells was demonstrated.

Key concepts: Stilbestrol, Diethylstilbestrol, Hemolysis, Hormone, Endocrinology, Steroid, Internal medicine, In vitro

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