2014Unpublished venueRequires access

The Anti-Diabetic Effect of Ethanol Leaf-Extract of Allium sativum on Albino Rats

U. Alum Esther

Open publisher page 7 citations

Abstract

The anti-diabetic effect of ethanol leaf-extract of Allium sativum was investigated on 24 albino rats. The animals were grouped into four (A, B, C and D) containing six rats each. Diabetes was induced by intraperitonial administration of alloxan solution at 100mg/kg body weights to the experimental animals. The ethanol leaf-extract of Allium sativum was administered to the animals in groups A, B, C and D at 200mg/kg, 400mg/kg, 600mg/kg and 0mg/kg body weights respectively for two weeks through oral intubation. Blood samples were collected after the two-week period of administration of the extract. The ethanol leaf-extract of Allium sativum significantly (p<0.05) and dose-dependently reduced blood glucose concentration in albino rats.

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What this paper is about

The anti-diabetic effect of ethanol leaf-extract of Allium sativum was investigated on 24 albino rats. The animals were grouped into four (A, B, C and D) containing six rats each. Diabetes was induced by intraperitonial administration of alloxan solution at 100mg/kg body weights to the experimental animals. The ethanol leaf-extract of Allium sativum was administered to the animals in groups A, B, C and D at 200mg/kg, 400mg/kg, 600mg/kg and 0mg/kg body weights respectively for two weeks through oral intubation. Blood samples were collected after the two-week period of administration of the extract. The ethanol leaf-extract of Allium sativum significantly (p<0.05) and dose-dependently reduced blood glucose concentration in albino rats.

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Available abstract

The anti-diabetic effect of ethanol leaf-extract of Allium sativum was investigated on 24 albino rats. The animals were grouped into four (A, B, C and D) containing six rats each. Diabetes was induced by intraperitonial administration of alloxan solution at 100mg/kg body weights to the experimental animals. The ethanol leaf-extract of Allium sativum was administered to the animals in groups A, B, C and D at 200mg/kg, 400mg/kg, 600mg/kg and 0mg/kg body weights respectively for two weeks through oral intubation. Blood samples were collected after the two-week period of administration of the extract. The ethanol leaf-extract of Allium sativum significantly (p<0.05) and dose-dependently reduced blood glucose concentration in albino rats.

Key concepts: Allium sativum, Sativum, Ethanol, Alloxan, Traditional medicine, Allium, Diabetes mellitus, Chemistry

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