Role of Insulin Resistance in Non Alcoholic Fatty Liver in Obese Type-2 Diabetic Subjects

Non alcoholic fatty liver disease (NAFLD) is a fatty liver disease occurring in patients without alcohol consumption. It includes a broad spectrum of liver disease, from fatty infiltration, inflammation and cirrhosis and is associated with obesity, hyperlipidemia and diabetes mellitus.An increase in the BMI and levels of FBS, total cholesterol, triglycerides, HDL, LDL, VLDL, SGPT, ALP, GGT, fasting insulin and hs CRP level and a decrease in HDL was observed in non alcoholic fatty liver group. Obesity, hyperglycemia, dyslipidemia and elevated liver enzymes, fasting insulin and hs CRP level are seen more frequently in non alcoholic fatty liver in type-2 diabetic obese patients.