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2016•Current Pharmaceutical DesignRequires access

Epidemiology, Prognosis and Prevention of Non-Traumatic Intracerebral Hemorrhage

Christian Weimar, Julian Kleine‐Borgmann

Open publisher page 70 citations

Abstract

BACKGROUND: Spontaneous non-traumatic intracerebral hemorrhage (ICH) has a worse prognosis than ischemic stroke. The purpose of this review was to update the reader on epidemiology, prognosis and secondary prevention strategies of ICH. METHODS: We performed a selected review from the literature including recent original articles and meta-analyses. RESULTS: ICH has an overall incidence of 24.6 per 100.000 patient years, which is considerably higher in Asian populations. Despite some progress in acute interventions and a great increase in clinical studies over the last decade, mortality of ICH remains high. In addition, survivors remain at increased risk of recurrent hemorrhagic as well as ischemic stroke. CONCLUSION: Knowledge on risk factors and prevention strategies can greatly decrease the incidence of ICH and improve prognosis of ICH survivors.

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What this paper is about

BACKGROUND: Spontaneous non-traumatic intracerebral hemorrhage (ICH) has a worse prognosis than ischemic stroke. The purpose of this review was to update the reader on epidemiology, prognosis and secondary prevention strategies of ICH. METHODS: We performed a selected review from the literature including recent original articles and meta-analyses. RESULTS: ICH has an overall incidence of 24.6 per 100.000 patient years, which is considerably higher in Asian populations. Despite some progress in acute interventions and a great increase in clinical studies over the last decade, mortality of ICH remains high. In addition, survivors remain at increased risk of recurrent hemorrhagic as well as ischemic stroke. CONCLUSION: Knowledge on risk factors and prevention strategies can greatly decrease the incidence of ICH and improve prognosis of ICH survivors.

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Available abstract

BACKGROUND: Spontaneous non-traumatic intracerebral hemorrhage (ICH) has a worse prognosis than ischemic stroke. The purpose of this review was to update the reader on epidemiology, prognosis and secondary prevention strategies of ICH. METHODS: We performed a selected review from the literature including recent original articles and meta-analyses. RESULTS: ICH has an overall incidence of 24.6 per 100.000 patient years, which is considerably higher in Asian populations. Despite some progress in acute interventions and a great increase in clinical studies over the last decade, mortality of ICH remains high. In addition, survivors remain at increased risk of recurrent hemorrhagic as well as ischemic stroke. CONCLUSION: Knowledge on risk factors and prevention strategies can greatly decrease the incidence of ICH and improve prognosis of ICH survivors.

Key concepts: Intracerebral hemorrhage, Epidemiology, Medicine, Stroke (engine), Thrombosis, Secondary prevention, Intensive care medicine, Surgery

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Epidemiology, Prognosis and Prevention of Non-Traumatic Intracerebral Hemorrhage — Research Paper | ScholarLens