2016•International Journal of Particle TherapyOpen access
Robust Optimization for Intensity Modulated Proton Therapy Plans with Multi-Isocenter Large Fields
Li Liao, Gino J. Lim, Yupeng Li, Juan Yu, Narayan Sahoo, Heng Li, Michael T. Gillin, X Zhu, Anita Mahajan, Steven J. Frank, David R. Grosshans, Quynh‐Nhu Nguyen, Daniel R. Gomez, Xiaodong Zhang
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Abstract
We have developed a robust optimization approach for intensity modulated proton therapy treatment plans with multi-isocenter large fields. The method creates a low-gradient field dose in the junction regions to mitigate the impact caused by misalignment errors and is more efficient than the conventional junction shifting technique.