2015•PubMedRequires access

[The cultivation and migration in vitro of olfactory ensheathing cells from human olfactory mucosa].

Qiubei Zhu, Huanhai Liu, Juntian Lang, Peng Hu, Shuwei Zhao

Abstract

OBJECTIVE: To investigate the bionomics of the olfactory ensheathing cells (OECs) of human olfactory mucosa. METHOD: To separate and cultivate the OECs of human and rat olfactory mucosa. To observe the cell growth, cell grouping and cell migration in vitro of the two types of OECs. RESULT: Successfully separated and cultivated the OECs of human and rat olfactory mucosa. OECs of the human and rat olfactory mucosa had the similar cell growth, cell grouping and cell migration ability in vitro. CONCLUSION: OECs of the human and rat olfactory mucosa have the similar bionomics in vitro, as a result, OECs of the human olfactory mucosa could be a reliable source of cell transplant for nerve injury.

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Key concepts: Olfactory mucosa, Olfactory ensheathing glia, Biology, Olfactory system, Cell biology, In vitro, Anatomy, Neuroscience