[Analysis of nucleotide combinations in types of the control region of human mitochondrial DNA].

Nucleotide combinations of polymorphic sites of the mitochondrial DNA (mtDNA) control region were analyzed in human populations of different ethnic region. It was demonstrated that the combination of C and T at positions 16,126 and 16,294, respectively, of the mtDNA control region was specific for Caucasoids. In eastern Slavic mtDNA types, this combination of nucleotides was associated with nucleotide substitutions G-A at position 14,905 of the cytochrome b gene and T-C at position 16,519 of the control region. Results of phylogenetic analysis of the types of mtDNA control region were used to estimate the evolutionary position of Eastern Slavs Caucasoid populations.