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2005•Journal of Jilin UniversityRequires access

Mitochondrial DNA Analysis of Human Remains Found in Yinniugou Cemetery

Haijing Wang, Eun‐Jeong Chang

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Abstract

We studied ancient individuals buried in the Yinniugou cemetery of Inner Mongolia by molecular(biological) methods.We obtained five sequences of the hypervariable region Ⅰ(HVS-Ⅰ) of the mitochondrial(DNA)(mtDNA) control region and primarily assigned the sequences into haplogroups A,B,D,C or Z,respectively.A phylogenetic tree and a two-dimensional MDS plot were constructed based on pairwise F_(ST) values(calculated from mtDNA HVS-Ⅰ sequence data) between the Yinniugou population and 16 relative modern populations.The results show the affinity of the ancient population with eastern Asian populations in matrilineal lineage.

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What this paper is about

We studied ancient individuals buried in the Yinniugou cemetery of Inner Mongolia by molecular(biological) methods.We obtained five sequences of the hypervariable region Ⅰ(HVS-Ⅰ) of the mitochondrial(DNA)(mtDNA) control region and primarily assigned the sequences into haplogroups A,B,D,C or Z,respectively.A phylogenetic tree and a two-dimensional MDS plot were constructed based on pairwise F_(ST) values(calculated from mtDNA HVS-Ⅰ sequence data) between the Yinniugou population and 16 relative modern populations.The results show the affinity of the ancient population with eastern Asian populations in matrilineal lineage.

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Available abstract

We studied ancient individuals buried in the Yinniugou cemetery of Inner Mongolia by molecular(biological) methods.We obtained five sequences of the hypervariable region Ⅰ(HVS-Ⅰ) of the mitochondrial(DNA)(mtDNA) control region and primarily assigned the sequences into haplogroups A,B,D,C or Z,respectively.A phylogenetic tree and a two-dimensional MDS plot were constructed based on pairwise F_(ST) values(calculated from mtDNA HVS-Ⅰ sequence data) between the Yinniugou population and 16 relative modern populations.The results show the affinity of the ancient population with eastern Asian populations in matrilineal lineage.

Key concepts: Mitochondrial DNA, Haplogroup, Hypervariable region, Phylogenetic tree, Ancient DNA, Lineage (genetic), mtDNA control region, Evolutionary biology

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