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Chimeras of the Gs alpha subunit that had the NH2- or COOH-terminal sequence substituted for the corresponding region of the Gi alpha subunit constitutively activate adenylyl cyclase.

Lynn E. Heasley, N. Dhanasekaran, Sunil Gupta, Shoji Osawa, Gary L. Johnson

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Key concepts: Adenylyl cyclase, G alpha subunit, Gi alpha subunit, Gs alpha subunit, Protein subunit, Interleukin 10 receptor, alpha subunit, Alpha (finance), Chemistry