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Comparison of ranitidine and cimetidine maintenance treatment of duodenal ulcer.

Walt Rp, Hunt Rh, Misiewicz Jj, I F Trotman, S Colley, Dewar Ep, Frost Ra, Shepherd Th, Golding Pl, Colin-Jones Dg

Abstract

Sixty-one patients with healed duodenal ulcer were studied during a 12-month maintenance trial with either 150 mg ranitidine at night or 400 mg cimetidine at night. Recurrences were determined at endoscopy after 6 and 12 months of treatment or because of symptomatic relapse. Ulcers recurred in 7 of 28 patients receiving ranitidine and in 8 of 33 patients receiving cimetidine. No serious side effects were encountered.

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Available abstract

Key concepts: Cimetidine, Ranitidine, Medicine, Duodenal ulcer, Gastroenterology, Endoscopy, Maintenance therapy, Internal medicine