1991•PubMedRequires access

Protective effect of cyproheptadine in a gerbil model of cerebral ischemia.

Claudia Caponnetto, Massimo Del Sette, Máyra Furlan, Carlo Gandolfo, Gianluigi Mancardi, Aldo L. Schenone, C Loeb

Abstract

The efficacy of Cyproheptadine, a serotonin antagonist, in preventing the cerebral ischemic damage was tested on experimental model of transient global cerebral ischemia in Mongolian Gerbil. The semi-quantitative histological evaluation of the severity of ischemic damage showed a protective effect of Cyproheptadine, mainly in the anterior cortical areas.

About this research paper

What this paper is about

Why it matters

OpenAlex reports 2 citations for this work. Citation counts describe recorded attention and do not establish research quality.

Key contribution

A contribution statement is not available in the OpenAlex record.

Method / approach

Method details are not available in the OpenAlex metadata.

Main findings

Findings are not separately available in the OpenAlex metadata.

Limitations

Limitations are not available in the OpenAlex metadata.

Applications

Application details are not available in the OpenAlex metadata.

Available abstract

Key concepts: Gerbil, Cyproheptadine, Ischemia, Medicine, Antagonist, Neurology, Rat model, Serotonin