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[An analysis of the stability of the antigenic structure in productive strain 205 of the tick-borne encephalitis virus during prolonged passage].

Maria R. Karpova, Iu V Fedorov

Abstract

The stability of the antigenic structure of tick-borne encephalitis (TBE) virus strain 205 in the process of passage through the brain of BALB/c mice has been studied. Its relationships with other viruses of the TBE complex have been analyzed with the use of monoclonal antibodies to virus proteins E and NS3. The stability of the protein structure of the virus has been determined by the immunofluorescence test and the enzyme immunoassay.

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Key concepts: Tick-borne encephalitis virus, Virology, Virus, Antigen, Biology, Encephalitis, Immunofluorescence, NS3