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[Liquid storage of thrombocytes: in vivo survival capability of thrombocytes after storage at +12 degrees C].

G Berndsen, Dirk Dekowski

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Abstract

Platelet concentrates were prepared from ACD-blood and stored at +12 degrees C for 3 days with gentle agitation. The viability of the platelets was estimated by autologous transfusion of 51chromium-labeled platelets into healthy volunteers. The in vivo recovery amounted to 33.5 +/- 6.9% and mean half survival time T0,5 was 1.1 ++/- 0.2 days on the 3rd day. The control values for freshly prepared platelet concentrates were 52.5 +/- 5.9% and T0.5 3.9 +/- 0.3 days. The decrease of viability due to lowering the temperature to +12 degrees C did not correspond to the pH-value, which was well maintained in the stored platelets.

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What this paper is about

Platelet concentrates were prepared from ACD-blood and stored at +12 degrees C for 3 days with gentle agitation. The viability of the platelets was estimated by autologous transfusion of 51chromium-labeled platelets into healthy volunteers. The in vivo recovery amounted to 33.5 +/- 6.9% and mean half survival time T0,5 was 1.1 ++/- 0.2 days on the 3rd day. The control values for freshly prepared platelet concentrates were 52.5 +/- 5.9% and T0.5 3.9 +/- 0.3 days. The decrease of viability due to lowering the temperature to +12 degrees C did not correspond to the pH-value, which was well maintained in the stored platelets.

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Available abstract

Platelet concentrates were prepared from ACD-blood and stored at +12 degrees C for 3 days with gentle agitation. The viability of the platelets was estimated by autologous transfusion of 51chromium-labeled platelets into healthy volunteers. The in vivo recovery amounted to 33.5 +/- 6.9% and mean half survival time T0,5 was 1.1 ++/- 0.2 days on the 3rd day. The control values for freshly prepared platelet concentrates were 52.5 +/- 5.9% and T0.5 3.9 +/- 0.3 days. The decrease of viability due to lowering the temperature to +12 degrees C did not correspond to the pH-value, which was well maintained in the stored platelets.

Key concepts: Platelet, In vivo, Blood preservation, Chemistry, Andrology, Platelet transfusion, Animal science, Surgery

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[Liquid storage of thrombocytes: in vivo survival capability of thrombocytes after storage at +12 degrees C]. — Research Paper | ScholarLens