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In Vitro and in Vivo Comparison of Single‐Donor Platelets and Multiple‐Donor Pooled Platelets Transfusions in Leukemic Patients

I. P. Patel, Edward P. Ambinder, J. F. Holland, LM Aledort

Open publisher page 19 citations

Abstract

In vitro and in vivo studies were done to evaluate efficacy of fresh, single donor platelets (SDP) obtained by Latham-bowl plateletpheresis and multiple donor, pooled platelets (MDPP) obtained by conventional centrifugation for transfusion of leukemic patients. Results indicate increased effectiveness, both in vitro and in vivo, of single donor platelets as compared to multiple donor pooled platelets.

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What this paper is about

In vitro and in vivo studies were done to evaluate efficacy of fresh, single donor platelets (SDP) obtained by Latham-bowl plateletpheresis and multiple donor, pooled platelets (MDPP) obtained by conventional centrifugation for transfusion of leukemic patients. Results indicate increased effectiveness, both in vitro and in vivo, of single donor platelets as compared to multiple donor pooled platelets.

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OpenAlex reports 19 citations for this work. Citation counts describe recorded attention and do not establish research quality.

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Available abstract

In vitro and in vivo studies were done to evaluate efficacy of fresh, single donor platelets (SDP) obtained by Latham-bowl plateletpheresis and multiple donor, pooled platelets (MDPP) obtained by conventional centrifugation for transfusion of leukemic patients. Results indicate increased effectiveness, both in vitro and in vivo, of single donor platelets as compared to multiple donor pooled platelets.

Key concepts: Plateletpheresis, Platelet, In vivo, In vitro, Platelet transfusion, Medicine, Immunology, Andrology

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In Vitro and in Vivo Comparison of Single‐Donor Platelets and Multiple‐Donor Pooled Platelets Transfusions in Leukemic Patients — Research Paper | ScholarLens