[Effectiveness of omeprazole therapy in children with gastroesophageal reflux diseases(GERD)].

THE AIM: Of the study was retrospective analysis of omeprazole (Polprazol) therapy efficacy in children with GERD. MATERIAL AND METHODS: The analyzed group consisted of 78 children with gastroesophageal reflux disease. GERD was detected on the base of questionnaire, pH-metry and/or endoscopy. The questionnaire was conducted in all patients, 24-hour pH-metric examination in 47% and endoscopy in 53% children. Than omeprazole therapy was introduced (0.5-1.0 mg/kg daily). RESULTS: Before omeprazole therapy rebounding was observed in 94% children, heartburn in 84%, vomits in 38% and abdominal pain in 90% children. After 8 weeks of therapy analyzed symptoms were significantly reduced--rebounding was observed in 31% children, heartburn in 28% vomits in 5% and abdominal pain in 26% children. CONCLUSION: Omeprazole therapy is effective in children with gastroesophageal reflux disease.