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Thermodynamic Study of Folate Analogue Binding to Dihydrofolate Reductases from Different Species

Sophie Sasso, Robert Gilli, Colette Lopez, Jean Claude Sari, Claudette Briand

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Key concepts: Dihydrofolate reductase, Antifolate, Methotrexate, Trimethoprim, Folic acid, Chemistry, Folic Acid Antagonists, Biochemistry

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