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[Prognostic evaluation of lymph node metastasis in thoracic esophageal cancer--an analysis of 212 cases].

Chen Jh, Wei Gq, Chen My

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Abstract

The authors studied retrospectively lymph node metastatic status impacts on survival of the 212 patients with thoracic esophageal squamous cell carcinoma and lymph node metastasis after curative resection. 663 (19.4%) of the total 3419 lymph nodes examined (an average of 16.1 per patient) were proved to be positive. The overall 5-year survival rate was 19.3%. The results showed that no difference in survival was observed in relation to the site of the involved lymph node. Difference in survival based on the number of metastatic lymph nodes (1 or > or = 2) and the frequency of positive nodes (< or = 10% or > 10%). The results indicate that staging of esophageal cancer should be made according to the absolute number and the relative frequency of lymph nodes involved. The effectiveness and limitation of extended lymph node dissection in relation to prognosis was discussed.

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What this paper is about

The authors studied retrospectively lymph node metastatic status impacts on survival of the 212 patients with thoracic esophageal squamous cell carcinoma and lymph node metastasis after curative resection. 663 (19.4%) of the total 3419 lymph nodes examined (an average of 16.1 per patient) were proved to be positive. The overall 5-year survival rate was 19.3%. The results showed that no difference in survival was observed in relation to the site of the involved lymph node. Difference in survival based on the number of metastatic lymph nodes (1 or > or = 2) and the frequency of positive nodes (< or = 10% or > 10%). The results indicate that staging of esophageal cancer should be made according to the absolute number and the relative frequency of lymph nodes involved. The effectiveness and limitation of extended lymph node dissection in relation to prognosis was discussed.

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Available abstract

The authors studied retrospectively lymph node metastatic status impacts on survival of the 212 patients with thoracic esophageal squamous cell carcinoma and lymph node metastasis after curative resection. 663 (19.4%) of the total 3419 lymph nodes examined (an average of 16.1 per patient) were proved to be positive. The overall 5-year survival rate was 19.3%. The results showed that no difference in survival was observed in relation to the site of the involved lymph node. Difference in survival based on the number of metastatic lymph nodes (1 or > or = 2) and the frequency of positive nodes (< or = 10% or > 10%). The results indicate that staging of esophageal cancer should be made according to the absolute number and the relative frequency of lymph nodes involved. The effectiveness and limitation of extended lymph node dissection in relation to prognosis was discussed.

Key concepts: Medicine, Lymph, Lymph node, Esophageal cancer, Dissection (medical), Lymph node metastasis, Survival rate, Carcinoma

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[Prognostic evaluation of lymph node metastasis in thoracic esophageal cancer--an analysis of 212 cases]. — Research Paper | ScholarLens