1995•Chinese Journal of Cancer ResearchRequires access
A prognostic evaluation on esophageal carcinoma with lymph node metastasis —An analysis of 212 cases
Chen Jianhua, Wang Wenguang, Wei Gongquan, Chen Mingyao, Zhongren Gao, Jinliang Xu, Cheng Jin-hua
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Abstract
The authors studied retrospectively lymph node metastatic status impacting on survival of 212 patients with thoracic esophageal squamous cell carcinoma 663 (19.4%) of the total 3, 419 lymph nodes examined (an average of 16.1 per patient) were proved to be positive. The overall 5-year survival rate was 19.3% (41/212). The results showed that no difference in survival was observed in relation to the site of the involved lymph node. Difference in survival based on the number of metastatic lymph nodes (1 or ≥2) and the frequence of positive nodes ≤10% or >10%) is statistically significant. The results indicated that the clinical staging of esophageal carcinoma should be made according to the absolute number and the relative frequency of lymph nodes involved. The effectiveness and limitation of extended lymph node dissection in relation to prognosis was discussed.