2010PubMedRequires access

[Intraoperative anaphylactic shock during renal transplantation].

Souichiro Fukushima, Hironobu Noguchi, Kohji Teruya, Manabu Kakinohana, Kazuhiro Sugahara

Open publisher page 1 citations

Abstract

A 32-year-old patient developed anaphylactic shock following the intravenous administration of fresh frozen plasma (FFP) during renal transplantation. The shock was reversed by intravenous adrenaline injection after stopping infusion of FFP. After the recovery from the shock state, all surgical procedures were done uneventfully and the renal function after transplantation was stable within normal ranges. Serum histamine and tryptase concentrations were significantly elevated during and immediately after the anaphylactic reaction. Although intracutaneous test could not be carried out with the FFP, we concluded that this anaphylactic shock was due to the FFP.

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What this paper is about

A 32-year-old patient developed anaphylactic shock following the intravenous administration of fresh frozen plasma (FFP) during renal transplantation. The shock was reversed by intravenous adrenaline injection after stopping infusion of FFP. After the recovery from the shock state, all surgical procedures were done uneventfully and the renal function after transplantation was stable within normal ranges. Serum histamine and tryptase concentrations were significantly elevated during and immediately after the anaphylactic reaction. Although intracutaneous test could not be carried out with the FFP, we concluded that this anaphylactic shock was due to the FFP.

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Available abstract

A 32-year-old patient developed anaphylactic shock following the intravenous administration of fresh frozen plasma (FFP) during renal transplantation. The shock was reversed by intravenous adrenaline injection after stopping infusion of FFP. After the recovery from the shock state, all surgical procedures were done uneventfully and the renal function after transplantation was stable within normal ranges. Serum histamine and tryptase concentrations were significantly elevated during and immediately after the anaphylactic reaction. Although intracutaneous test could not be carried out with the FFP, we concluded that this anaphylactic shock was due to the FFP.

Key concepts: Medicine, Anaphylactic shock, Shock (circulatory), Transplantation, Tryptase, Anesthesia, Anaphylaxis, Fresh frozen plasma

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