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[Current reviews in aptamers].

Chenggang Wang, Zhihong Mo

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Abstract

Aptamers are oligo-nucleotides which are selected by SELEX (systematic evolution of ligands by exponential enrichment) in vitro, it can bind protein or other small molecules with high specificity and affinity. Researches on aptamers have achieved much progress in biosensor, drug development and nano technology. This article has reviewed the researches and applications of aptamers in the past two years.

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What this paper is about

Aptamers are oligo-nucleotides which are selected by SELEX (systematic evolution of ligands by exponential enrichment) in vitro, it can bind protein or other small molecules with high specificity and affinity. Researches on aptamers have achieved much progress in biosensor, drug development and nano technology. This article has reviewed the researches and applications of aptamers in the past two years.

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Available abstract

Aptamers are oligo-nucleotides which are selected by SELEX (systematic evolution of ligands by exponential enrichment) in vitro, it can bind protein or other small molecules with high specificity and affinity. Researches on aptamers have achieved much progress in biosensor, drug development and nano technology. This article has reviewed the researches and applications of aptamers in the past two years.

Key concepts: Aptamer, Systematic evolution of ligands by exponential enrichment, Biosensor, Computational biology, Nanotechnology, SELEX Aptamer Technique, Chemistry, Biology

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