[Clinical experience of spontaneous breathing trial in weaning mechanical ventilation].

OBJECTIVE: To compare the spontaneous breathing trial (SBT) weaning mode with the classical weaning mode for extubation in patients undergoing mechanical ventilation. METHODS: Fifty-seven patients showing stabilized condition after mechanical ventilation, were divided into two groups. In 21 patients, admitted from June 2004 to December 2005, a gradual decrease in respiratory support as the mode of weaning of mechanical ventilation. In 36 patients, admitted from January 2006 to March 2007, SBT weaning mode was adopted. The length of mechanical ventilation and stay in intensive care unit (ICU), ventilator-associated pneumonia (VAP) rate, retubing rate in 48 hours, ICU mortality were compared between two groups. RESULTS: The length of mechanical ventilation were (59.4+/-37.1) hours and (111.4+/-59.8) hours (P=0.001), length of stay in ICU were (8.0+/-5.5) days and (15.3+/-14.3) days (P=0.034), VAP rate was 16.7% and 38.0% (P=0.070), retubing rate in 48 hours were 19.4% and 5.0% (P=0.253), ICU mortality rate was 25.0% and 24.0% (P=0.920) in SBT group and control group, respectively. CONCLUSION: The SBT weaning mode shortens the time of mechanical ventilation and the ICU stay days. Both groups have the identical VAP rate, retubing rate in 48 hours, and ICU mortality.