2002•PubMedRequires access

[Effect of gamma-aminobutyric acid on the sperm acrosin activity].

Shu-Ling Bian, Wei Zhang, Hui Zhu, Ni Jiang, Lan-Chun Yao, Liang Chen

Abstract

OBJECTIVES: To investigate the effect of gamma-aminobutyric acid (GABA) on the sperm acrosin activity in normal men and positive antisperm antibody (AsAb) men. METHODS: Sperm acrosin activity was detected by BAEE/ADH method. RESULTS: GABA could increase the sperm acrosin activity in normal and AsAb positive patients (P < 0.01). The results also indicated that GABA significantly increased Na(+)-K(+)-ATPase activity (P < 0.01), Ca(2+)-ATPase activity (P < 0.05) and SOD activity (P < 0.01) of sperm. CONCLUSIONS: The results demonstrated that GABA could influence the sperm acrosin activity.

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Key concepts: Acrosin, Sperm, Chemistry, Aminobutyric acid, Andrology, Endocrinology, Internal medicine, Biology