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1974•Thrombosis and HaemostasisRequires access

Measurement of the Rate of Clot Retraction

Michio Itoh, Yoshihisa NISHIMURA, Osamu Takenaka, Yǔji Inada

Open publisher page 6 citations

Abstract

Summary The volume of serum exuded from clot was measured with time in the presence of platelets. The change of the volume of clot followed the first order kinetics with respect to time and the rate constant (k) was introduced to assay for clot retraction. The value of k and maximal serum volume exuded from clot, Vf, are dependent on the number of platelets, but the way k depends on the number of platelets is different from that Vf does on it. This suggests that these two parameters reflect the different phases of clot retraction.

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What this paper is about

Summary The volume of serum exuded from clot was measured with time in the presence of platelets. The change of the volume of clot followed the first order kinetics with respect to time and the rate constant (k) was introduced to assay for clot retraction. The value of k and maximal serum volume exuded from clot, Vf, are dependent on the number of platelets, but the way k depends on the number of platelets is different from that Vf does on it. This suggests that these two parameters reflect the different phases of clot retraction.

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Available abstract

Summary The volume of serum exuded from clot was measured with time in the presence of platelets. The change of the volume of clot followed the first order kinetics with respect to time and the rate constant (k) was introduced to assay for clot retraction. The value of k and maximal serum volume exuded from clot, Vf, are dependent on the number of platelets, but the way k depends on the number of platelets is different from that Vf does on it. This suggests that these two parameters reflect the different phases of clot retraction.

Key concepts: Clot retraction, Platelet, Clot formation, Volume (thermodynamics), Chemistry, Mean platelet volume, Cardiology, Thrombosis

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