ScholarLens Back to search
2015•PubMedRequires access

[RESEARCH PROGRESS OF microRNA IN INTERVERTEBRAL DISC DEGENERATION].

Xinhua Li, Jian Cui, Gui-Xin Sun, Jun Tan, Lijun Li

Open publisher page 1 citations

Abstract

OBJECTIVE: To comprehensively analyze the relationship between microRNAs and intervertebral disc degeneration at home and abroad. METHODS: The literature about the relationship between microRNAs and intervertebral disc degeneration was reviewed and analyzed. RESULTS: MicroRNA can lead to intervertebral disc degeneration by regulating the gene expression, thus influencing the cell's apoptosis and proliferation, increasing of the production of inflammatory mediator and protease, which play important roles in intervertebral disc degeneration. CONCLUSION: MicroRNA is a research focus in the field of intervertebral disc degeneration. Further research of the relationship between microRNAs and intervertebral disc degeneration will help to identify the pathogenesis of intervertebral disc degeneration and furnish the new ideal for the diagnosis and treatment of intervertebral disc degeneration.

About this research paper

What this paper is about

OBJECTIVE: To comprehensively analyze the relationship between microRNAs and intervertebral disc degeneration at home and abroad. METHODS: The literature about the relationship between microRNAs and intervertebral disc degeneration was reviewed and analyzed. RESULTS: MicroRNA can lead to intervertebral disc degeneration by regulating the gene expression, thus influencing the cell's apoptosis and proliferation, increasing of the production of inflammatory mediator and protease, which play important roles in intervertebral disc degeneration. CONCLUSION: MicroRNA is a research focus in the field of intervertebral disc degeneration. Further research of the relationship between microRNAs and intervertebral disc degeneration will help to identify the pathogenesis of intervertebral disc degeneration and furnish the new ideal for the diagnosis and treatment of intervertebral disc degeneration.

Why it matters

OpenAlex reports 1 citations for this work. Citation counts describe recorded attention and do not establish research quality.

Key contribution

A contribution statement is not available in the OpenAlex record.

Method / approach

Method details are not available in the OpenAlex metadata.

Main findings

Findings are not separately available in the OpenAlex metadata.

Limitations

Limitations are not available in the OpenAlex metadata.

Applications

Application details are not available in the OpenAlex metadata.

Available abstract

OBJECTIVE: To comprehensively analyze the relationship between microRNAs and intervertebral disc degeneration at home and abroad. METHODS: The literature about the relationship between microRNAs and intervertebral disc degeneration was reviewed and analyzed. RESULTS: MicroRNA can lead to intervertebral disc degeneration by regulating the gene expression, thus influencing the cell's apoptosis and proliferation, increasing of the production of inflammatory mediator and protease, which play important roles in intervertebral disc degeneration. CONCLUSION: MicroRNA is a research focus in the field of intervertebral disc degeneration. Further research of the relationship between microRNAs and intervertebral disc degeneration will help to identify the pathogenesis of intervertebral disc degeneration and furnish the new ideal for the diagnosis and treatment of intervertebral disc degeneration.

Key concepts: Intervertebral disc, Degeneration (medical), microRNA, Intervertebral disk, Pathology, Medicine, Anatomy, Biology

Related papers

Related paper 1Related paper 2Related paper 3
Back to paper searchBrowse research topicsOriginal source
[RESEARCH PROGRESS OF microRNA IN INTERVERTEBRAL DISC DEGENERATION]. — Research Paper | ScholarLens