[A case of successful combination therapy with trans-arterial embolization, trans-arterial chemotherapy and radiofrequency ablation therapy].

A patient is a 78-year-old male. Abdominal ultrasound tomography revealed hepatic tumors. Abdominal computer tomography (CT) revealed a 5.5 cm-in-diameter low enhanced lesion and a 4.0 cm-in-diameter enhanced lesion at S8, and a 1.8 cm-in-diameter enhanced lesion at S5, a 1.4 cm-in-diameter enhanced lesion at S6, which led to a diagnosis of combined hepatocellular carcinoma with intra-hepatic metastasis (IM2) in July 2007. From August to October 2006, he received a hepatic combination therapy with trans-arterial chemotherapy at a low enhanced lesion and trans-arterial embolization (TAE), and radiofrequency ablation therapy (RFA) at enhanced lesions. As of June 2008, this patient is still alive with no recurrence after 8 months from the beginning of this treatment. In conclusion, it might have been effective and suitable to combine multiple therapies to each of the tumor characteristics for mixed hepatocellular carcinoma.