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Developments in histocompatibility testing.

Arne Svejgaard, Mogens Thomsen

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Abstract

Recent progress in HLA typing involves new methods which allow typing for MLC (mixed lymphocyte culture) and Ia (immune associated) antigens. These antigens seem to play a major role in transplant rejection in HLA non-immunised patients. When the new typing methods eventually become applied in matching of kidneys it seems likely that the results of kidney transplantation will be significantly improved.

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What this paper is about

Recent progress in HLA typing involves new methods which allow typing for MLC (mixed lymphocyte culture) and Ia (immune associated) antigens. These antigens seem to play a major role in transplant rejection in HLA non-immunised patients. When the new typing methods eventually become applied in matching of kidneys it seems likely that the results of kidney transplantation will be significantly improved.

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Available abstract

Recent progress in HLA typing involves new methods which allow typing for MLC (mixed lymphocyte culture) and Ia (immune associated) antigens. These antigens seem to play a major role in transplant rejection in HLA non-immunised patients. When the new typing methods eventually become applied in matching of kidneys it seems likely that the results of kidney transplantation will be significantly improved.

Key concepts: Typing, Human leukocyte antigen, Histocompatibility, Histocompatibility Testing, Tissue typing, Immunology, Antigen, Immune system

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