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2018•Molecular and experimental biology in medicineOpen access

PROSPECTIVE HLA-DP TYPING OF A CADAVERIC ORGAN DONOR FOR KIDNEY TRANSPLANTATION – A CASE REPORT

Marija Burek Kamenarić, Marija Maskalan, Ivana Kovačević Vojtušek, Zorana Grubić, Renata Žunec

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Abstract

In this paper, we present the case of an HLA-DP immunized patient in the process of kidney re-transplantation for which potential pre-transplantation HLA-DP donor-specific antibodies were detected. For that reason, for the first time in our laboratory practice, prospective cadaveric donor HLA-DP typing was performed during the process of kidney allocation. This case, together with other international study reports and protocols of some transplantation programs, points to the importance of introducing pre-transplant HLA-DP typing in cadaveric kidney transplantation in Croatia.

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What this paper is about

In this paper, we present the case of an HLA-DP immunized patient in the process of kidney re-transplantation for which potential pre-transplantation HLA-DP donor-specific antibodies were detected. For that reason, for the first time in our laboratory practice, prospective cadaveric donor HLA-DP typing was performed during the process of kidney allocation. This case, together with other international study reports and protocols of some transplantation programs, points to the importance of introducing pre-transplant HLA-DP typing in cadaveric kidney transplantation in Croatia.

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Available abstract

In this paper, we present the case of an HLA-DP immunized patient in the process of kidney re-transplantation for which potential pre-transplantation HLA-DP donor-specific antibodies were detected. For that reason, for the first time in our laboratory practice, prospective cadaveric donor HLA-DP typing was performed during the process of kidney allocation. This case, together with other international study reports and protocols of some transplantation programs, points to the importance of introducing pre-transplant HLA-DP typing in cadaveric kidney transplantation in Croatia.

Key concepts: Cadaveric spasm, Transplantation, Human leukocyte antigen, Tissue typing, Kidney transplantation, Typing, Medicine, Histocompatibility Testing

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