Two Cases of Relapsed Primary Cutaneous CD30 Positive Large Cell Lymphoma

The clinical characteristics of primary cutaneous CD30-positive large cell lymphoma are solitary or localized skin lesions, frequent relapses, spontaneous regression and a favorable prognosis. These relapses and spontaneous regressions occur frequently in borderline cases between CD30-positive large cell lymphoma and lymphomatoid papulosis. Regression and relapse, which occurs in both cutaneous CD30 positive large cell lymphoma and lymphomatoid papulosis, dose not help distinguish one from the other. We report two cases diagnosed as clinically and histologically primary cutaneous CD30-positive large cell lymphoma, recurred respectively on the same anatomic site and on the different anatomic site.