2001•PubMedRequires access

[Study on the chemosensitivity test of human gastric cancer using the MTT assay].

Z Chen, Jianran Hu, J Chen, Yan Lu, Y.-t. Mao, Lian Zou

Abstract

OBJECTIVE: This study was conducted to investigate the chemosensitivity of gastric carcinoma. METHODS: 112 cases of fresh human gastric cancer samples were obtained for drug sensitivity testing using MTT. RESULTS: The sensitivity sequence of antitumor agents was 5-Fu, DDP, MMC, etc. On the other hand, the sensitivity was relative to pathology and individual differences. CONCLUSION: The MTT assay is an accurate system for determination of the chemosensitivity of tumor cells.

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Key concepts: Chemosensitivity assay, MTT assay, Gastric carcinoma, Cancer, Oncology, Medicine, Cancer research, Internal medicine