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The experimental contribution to the study of the portal circulation by means of dynamic hepatobiliary scintigraphy.

J Králík, M Mysliveček, Č Neoral, J Dušek, T Grosmanová, F Sprucek

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Abstract

Report is given on a group of dogs the portal vein of which was narrowed to 1/5 by putting on a metal spiral. A disorder of the circulation of the portal blood induced in this way was followed by opening of the effective hepatofugal collaterals and forming of slight portal hypertension without clinical manifestation. The changed portal circulation was studied by means of dynamic hepatobiliary scintigraphy within 12 months. It was found out that the curve of progression of the isotope through the liver had been changed in a way which corresponded to slowing of perfusion of the liver by the portal blood. It is analogous to observation of patients with PPH and its verification. The study is documented by morphological, X-ray and isotopic methods.

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What this paper is about

Report is given on a group of dogs the portal vein of which was narrowed to 1/5 by putting on a metal spiral. A disorder of the circulation of the portal blood induced in this way was followed by opening of the effective hepatofugal collaterals and forming of slight portal hypertension without clinical manifestation. The changed portal circulation was studied by means of dynamic hepatobiliary scintigraphy within 12 months. It was found out that the curve of progression of the isotope through the liver had been changed in a way which corresponded to slowing of perfusion of the liver by the portal blood. It is analogous to observation of patients with PPH and its verification. The study is documented by morphological, X-ray and isotopic methods.

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Available abstract

Report is given on a group of dogs the portal vein of which was narrowed to 1/5 by putting on a metal spiral. A disorder of the circulation of the portal blood induced in this way was followed by opening of the effective hepatofugal collaterals and forming of slight portal hypertension without clinical manifestation. The changed portal circulation was studied by means of dynamic hepatobiliary scintigraphy within 12 months. It was found out that the curve of progression of the isotope through the liver had been changed in a way which corresponded to slowing of perfusion of the liver by the portal blood. It is analogous to observation of patients with PPH and its verification. The study is documented by morphological, X-ray and isotopic methods.

Key concepts: Portal circulation, Scintigraphy, Portal hypertension, Medicine, Portal vein, Perfusion, Blood circulation, Technetium

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The experimental contribution to the study of the portal circulation by means of dynamic hepatobiliary scintigraphy. — Research Paper | ScholarLens