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[The result of adjuvant chemotherapy of colorectal cancer].

Shiian Rd

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Abstract

In 103 patients with colorectal cancer the efficacy of three schedules of chemotherapy using fluorouracil (FU), FU with doxorubicin, FU with levamizol (LEV) was studied up. The result of treatment in 3 and 5 years was compared with that in patients, to whom merely surgical treatment was performed. Most effective treatment was application of FU with LEV: the three-year survival index of patients had constituted 66.7%, five-year one--54.5% and in control group--46.8 and 41.3% accordingly. The adjuvant chemotherapy performance was most effective in cancer stage III and in nondifferentiated type of tumor.

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What this paper is about

In 103 patients with colorectal cancer the efficacy of three schedules of chemotherapy using fluorouracil (FU), FU with doxorubicin, FU with levamizol (LEV) was studied up. The result of treatment in 3 and 5 years was compared with that in patients, to whom merely surgical treatment was performed. Most effective treatment was application of FU with LEV: the three-year survival index of patients had constituted 66.7%, five-year one--54.5% and in control group--46.8 and 41.3% accordingly. The adjuvant chemotherapy performance was most effective in cancer stage III and in nondifferentiated type of tumor.

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Available abstract

In 103 patients with colorectal cancer the efficacy of three schedules of chemotherapy using fluorouracil (FU), FU with doxorubicin, FU with levamizol (LEV) was studied up. The result of treatment in 3 and 5 years was compared with that in patients, to whom merely surgical treatment was performed. Most effective treatment was application of FU with LEV: the three-year survival index of patients had constituted 66.7%, five-year one--54.5% and in control group--46.8 and 41.3% accordingly. The adjuvant chemotherapy performance was most effective in cancer stage III and in nondifferentiated type of tumor.

Key concepts: Medicine, Fluorouracil, Colorectal cancer, Chemotherapy, Doxorubicin, Adjuvant chemotherapy, Adjuvant, Internal medicine

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[The result of adjuvant chemotherapy of colorectal cancer]. — Research Paper | ScholarLens