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[Relationship between the expression of uncoupling protein 2 and insulin resistance in fatty liver rats induced by high-fat food].

Yuanyuan Chen, Yuan Li, Zhu Lian, Yinhua Chen, Bei Zhang

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Abstract

本研究通过高脂饮食喂养大鼠,观察大鼠肝内脂肪沉积情况,同时检测肝细胞解偶联蛋白2(UCP-2)和胰岛素信号分子胰岛素受体底物2(IRS-2)mRNA的表达,以探讨在非酒精性脂肪性肝病(NAFLD)发病中胰岛素抵抗与肝细胞U CP2表达的关联及其作用机制。

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What this paper is about

本研究通过高脂饮食喂养大鼠,观察大鼠肝内脂肪沉积情况,同时检测肝细胞解偶联蛋白2(UCP-2)和胰岛素信号分子胰岛素受体底物2(IRS-2)mRNA的表达,以探讨在非酒精性脂肪性肝病(NAFLD)发病中胰岛素抵抗与肝细胞U CP2表达的关联及其作用机制。

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Available abstract

本研究通过高脂饮食喂养大鼠,观察大鼠肝内脂肪沉积情况,同时检测肝细胞解偶联蛋白2(UCP-2)和胰岛素信号分子胰岛素受体底物2(IRS-2)mRNA的表达,以探讨在非酒精性脂肪性肝病(NAFLD)发病中胰岛素抵抗与肝细胞U CP2表达的关联及其作用机制。

Key concepts: Insulin resistance, Uncoupling protein, Internal medicine, Endocrinology, Fatty liver, Chemistry, Insulin, Biology

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[Relationship between the expression of uncoupling protein 2 and insulin resistance in fatty liver rats induced by high-fat food]. — Research Paper | ScholarLens