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2017•Paediatrica IndonesianaOpen access

The Treatment of Tuberculous Meningitis in Children with A Combination of Isoniazid, Rifampicin and Streptomycin (A preliminary report)

Nastitin Rahajoe, Noenoeng Rahajoe, Imam Boediman, Mardjanis Said, Sinan Vidi Lazuardi

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Abstract

Twenty-two cases of tuberculous meningitis have been treated with isoniazid, streptomycin and rifampicin and 19 cases with isoniazid, P.A.S. and streptomycin. Both groups received corticosteroid at the beginning of the treatment. The 2 groups were compared on the clinical and neurological improvement, duration of necessary hospitalization, the presence of sequelae, and the death rate. Also the tolerability of both regimens was compared.

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Twenty-two cases of tuberculous meningitis have been treated with isoniazid, streptomycin and rifampicin and 19 cases with isoniazid, P.A.S. and streptomycin. Both groups received corticosteroid at the beginning of the treatment. The 2 groups were compared on the clinical and neurological improvement, duration of necessary hospitalization, the presence of sequelae, and the death rate. Also the tolerability of both regimens was compared.

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Available abstract

Twenty-two cases of tuberculous meningitis have been treated with isoniazid, streptomycin and rifampicin and 19 cases with isoniazid, P.A.S. and streptomycin. Both groups received corticosteroid at the beginning of the treatment. The 2 groups were compared on the clinical and neurological improvement, duration of necessary hospitalization, the presence of sequelae, and the death rate. Also the tolerability of both regimens was compared.

Key concepts: Medicine, Tuberculous meningitis, Streptomycin, Isoniazid, Rifampicin, Tolerability, Meningitis, Tuberculosis

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