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[The rebound of nasal resistance after decongestant used in nose].

Jasper Shen, X Huang, Jing Xiang, Huijun Shu

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Abstract

OBJECTIVE: To investigate the effect of decongestant on nasal resistance so as to provide theories for studing rhinitis medicamentosa. METHOD: The changes of nasal blockage in 92 cases of acute rhinitis and chronic rhinitis after using decongestants were recorded, and the nasal resistance in 39 cases were measured by active anterior rhinomanometry. RESULT: According to the diseases and decongestants used, the percentage of nasal resistance rebound were 63.5%, 31.2%, 32.2%, 8.6% in 4 groups of investigated patients and 50%, 20%, 75% in 3 groups of measured patients respectively. CONCLUSION: Decongestants can cause the rebound of nasal resistance, which related to the diseases and the decongestants used. The mechanism may be that the factors dilating the vasa in nasal mucosa are activated.

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What this paper is about

OBJECTIVE: To investigate the effect of decongestant on nasal resistance so as to provide theories for studing rhinitis medicamentosa. METHOD: The changes of nasal blockage in 92 cases of acute rhinitis and chronic rhinitis after using decongestants were recorded, and the nasal resistance in 39 cases were measured by active anterior rhinomanometry. RESULT: According to the diseases and decongestants used, the percentage of nasal resistance rebound were 63.5%, 31.2%, 32.2%, 8.6% in 4 groups of investigated patients and 50%, 20%, 75% in 3 groups of measured patients respectively. CONCLUSION: Decongestants can cause the rebound of nasal resistance, which related to the diseases and the decongestants used. The mechanism may be that the factors dilating the vasa in nasal mucosa are activated.

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Available abstract

OBJECTIVE: To investigate the effect of decongestant on nasal resistance so as to provide theories for studing rhinitis medicamentosa. METHOD: The changes of nasal blockage in 92 cases of acute rhinitis and chronic rhinitis after using decongestants were recorded, and the nasal resistance in 39 cases were measured by active anterior rhinomanometry. RESULT: According to the diseases and decongestants used, the percentage of nasal resistance rebound were 63.5%, 31.2%, 32.2%, 8.6% in 4 groups of investigated patients and 50%, 20%, 75% in 3 groups of measured patients respectively. CONCLUSION: Decongestants can cause the rebound of nasal resistance, which related to the diseases and the decongestants used. The mechanism may be that the factors dilating the vasa in nasal mucosa are activated.

Key concepts: Nasal decongestant, Decongestant, Rhinomanometry, Medicine, Nose, Mucous membrane of nose, Pseudoephedrine, Anesthesia

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