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[Study on chemical constituents of triterpenoids from Potentilla discolor].

Yu-Yun Li, Cao-Mao Xiao, Ming Yao, Zeng Xian-yi, Xiaohua Xiao, Cai-Qing Zhu

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Abstract

OBJECTIVE: To study the triterpenoids constituents in Potentilla discolor. METHODS: The compounds were isolated by silica gel chromatography, macroporous resins and polyamide column chromatography from the 70% ethanol extract, and their structures were identified by spectral analysis. RESULTS: Six compounds were obtained and their structures were identified as 3-O-beta-D-glucopyranosyl-(1 --> 2) -beta-D-xylopyranosyl-19a-hydroxyurs-12-en-28-acid (1), 2alpha, 3/beta, 19alpha-trihydroxyurs-12-en-28-acid (2), 3beta, 19alpha-trihydroxyurs-12-en-24, 28-acid (3), 2alpha, 3beta-dihydroxyolean-12-en-28-acid (4), 2alpha, 3alpha, 19alpha-trihydroxyurs-12-en-28-acid (5), beta-sitosterol (6). CONCLUSION: Compounds 1 and 3 are obtained from this plant for the fisrt time.

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What this paper is about

OBJECTIVE: To study the triterpenoids constituents in Potentilla discolor. METHODS: The compounds were isolated by silica gel chromatography, macroporous resins and polyamide column chromatography from the 70% ethanol extract, and their structures were identified by spectral analysis. RESULTS: Six compounds were obtained and their structures were identified as 3-O-beta-D-glucopyranosyl-(1 --> 2) -beta-D-xylopyranosyl-19a-hydroxyurs-12-en-28-acid (1), 2alpha, 3/beta, 19alpha-trihydroxyurs-12-en-28-acid (2), 3beta, 19alpha-trihydroxyurs-12-en-24, 28-acid (3), 2alpha, 3beta-dihydroxyolean-12-en-28-acid (4), 2alpha, 3alpha, 19alpha-trihydroxyurs-12-en-28-acid (5), beta-sitosterol (6). CONCLUSION: Compounds 1 and 3 are obtained from this plant for the fisrt time.

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Available abstract

OBJECTIVE: To study the triterpenoids constituents in Potentilla discolor. METHODS: The compounds were isolated by silica gel chromatography, macroporous resins and polyamide column chromatography from the 70% ethanol extract, and their structures were identified by spectral analysis. RESULTS: Six compounds were obtained and their structures were identified as 3-O-beta-D-glucopyranosyl-(1 --> 2) -beta-D-xylopyranosyl-19a-hydroxyurs-12-en-28-acid (1), 2alpha, 3/beta, 19alpha-trihydroxyurs-12-en-28-acid (2), 3beta, 19alpha-trihydroxyurs-12-en-24, 28-acid (3), 2alpha, 3beta-dihydroxyolean-12-en-28-acid (4), 2alpha, 3alpha, 19alpha-trihydroxyurs-12-en-28-acid (5), beta-sitosterol (6). CONCLUSION: Compounds 1 and 3 are obtained from this plant for the fisrt time.

Key concepts: Potentilla, Silica gel, Triterpenoid, Polyamide, Chromatography, Chemistry, Column chromatography, Chemical constituents

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