[The influence exercised by various temperatures on platelet aggregation in vitro].
Massimo Rossi, Antonio Di Biagio, G Nubile
Abstract
Massimo Rossi, Antonio Di Biagio, G Nubile
Abstract
To obtain a regular haemostasis is necessary that the platelets are numerically sufficient and functionally normal. Many factors influence on platelet aggregation; among these platelet shape, dimensions and volume. In our study we have analysed the temperature influence on platelet aggregation. In a group of 27 subjects we have demonstrated that the platelet rich plasma pre-incubation for 30 minutes in ice-bath does not modify the platelet aggregation capacity. On the contrary, the platelet rich plasma pre-incubation for 30 minutes at 37 degrees C reduces considerably the platelet aggregation, probably for the platelet volume reduction.
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To obtain a regular haemostasis is necessary that the platelets are numerically sufficient and functionally normal. Many factors influence on platelet aggregation; among these platelet shape, dimensions and volume. In our study we have analysed the temperature influence on platelet aggregation. In a group of 27 subjects we have demonstrated that the platelet rich plasma pre-incubation for 30 minutes in ice-bath does not modify the platelet aggregation capacity. On the contrary, the platelet rich plasma pre-incubation for 30 minutes at 37 degrees C reduces considerably the platelet aggregation, probably for the platelet volume reduction.
Key concepts: Platelet, Incubation, Platelet aggregation, Platelet-rich plasma, Chemistry, Biophysics, Mean platelet volume, In vitro