2014•PubMedRequires access

[Study on chemical constituents of iridoids from eucommiae folium].

Yue-ming Zuo, Zhongli Zhang, Yanyan Wang, Lanying Chen, Rong-Hua Liu, Yuyi Li

Abstract

OBJECTIVE: To investigate the chemical constituents of iridoids from Eucommiae Folium. METHODS: The compounds were isolated and purified by various column chromatography, the structures were identified on the basis of physiochemical properties and spectral analysis. RESULTS: Nine iridoids were isolated and identified as asperuloside (1), daphylloside (2), scandoside methyl ester (3), loganin (4), 8-epi-loganin (5), 7-epi-loganin (6), deacetyl asperulosidic acid methyl ester (7), geniposide (8) and geniposidic acid (9). CONCLUSION: Compounds 2 - 7 are isolated from this plant for the first time, compounds 4 - 6 are isolated from this genus for the first time.

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Key concepts: Loganin, Folium of Descartes, Chemistry, Chromatography, Chemical constituents, Iridoid, Traditional medicine, Botany